MESENTERIC ARTERY DISEASE

WHAT IS MESENTERIC ARTERY DISEASE

Narrowing of the arteries (blood vessels) that supply the body’s stomach and intestines

There are two types

  • Acute mesenteric ischemia- sudden block typically caused by a clot and can be immediately life-threatening.
  • Chronic mesenteric ischemia- related to atherosclerosis with a slower onset over many years.

Three main arteries that supply blood to your small and large intestine are known as the Coeliac trunk; Superior Mesenteric Artery and Inferior Mesenteric artery.

WHAT ARE THE CAUSES OF MESENTERIC ARTERY ISCHEMIA?

  • ACUTE – blood clots suddenly block blood flow.
  • These clots often originate in the heart and are more common among patients with an irregular heartbeat or heart disease.
  • CHRONIC-  atherosclerosis (hardening of the arteries)slows the amount of blood flowing.

WHAT ARE THE SYMPTOMS?

  • Acute – Sudden severe abdominal pain.
  • CHRONIC- severe stomach pain 15–60 minutes after eating.
  • Pain may last for as long as 2 hours.
  • Recur with every meal.
  • Nausea, vomiting, diarrhea, or flatulence.
  • Fear of food (Food fright) may develop due to pain.
  • Unintentional Weight Loss.

HOW IS A DIAGNOSIS MADE?

A computed tomography (CT) scan is the test of choice. A CTAngiogram creates detailed three-dimensional images of cross-sections of your body. These images can identify problems with your arteries or with your abdominal organs.

HOW IS THIS TREATED?

  • The goal of treatment -to re-open the artery to allow adequate blood flow to your intestine so it will work properly.
  • Must be accomplished before permanent damage is done.

 

IN ACUTE CASE

  1. Usually, an emergency procedure since severe intestinal damage can occur rapidly.
  2. Open surgery- to remove the clot and look for damage to the intestines and assess its viability.
  3. Clot aspiration- a new minimally invasive modality where the clot is sucked out using negative pressure.
  4. Thrombolytic therapy- to dissolve the clot, strong blood thinners are given directly into the artery during an angiogram.

IN CHRONIC CASE

  • Minimally invasive endovascular treatment.
  • the first-line approach in most instances.
  • Balloon angioplasty and stenting.
  • Bypass surgery- creates a detour around the narrowed or blocked section of the affected artery. To create the detour, one of your veins or a synthetic tube is used as a graft, sewn-in above and below the blocked area to restore adequate blood flow to your intestines.

STAYING HEALTHY

  1. Follow a heart-healthy diet.
  2. Avoid smoking.
  3. Exercise regularly.
  4. Stay hydrated.
  5. Manage chronic medical conditions including diabetes, high blood pressure, kidney failure, and heart disease.