Upper Limb Ischemia

Introduction
Plaque buildup in the arteries(called atherosclerosis) that carry blood to your head, organs, and limbs
Plaque is made up of fat, cholesterol, calcium, fibrous tissue can harden and narrow the arteries
Limits the flow of oxygen-rich blood from your heart to your hands, legs, head, kidneys and stomach
Here we will here focus on P.A.D. that affects blood flow to the hands.
Less common than Lower Limb Disease due to the arms’ closer proximity to the heart, and the fact that most patients are asymptomatic
Causes
- Smoking
- Diabetes
- High amounts of certain fats and cholesterol in the blood
- Tobacco usage in any form
- High blood pressure
- Inherent blood clotting issues
- Old age
- Obesity
- Thoracic Outlet syndrome
- Raynauds syndrome
- Idiopathic(unknown)
Eventually, a section of plaque can rupture (break open), causing a blood clot to form at the site
Types
Acute- Sudden block of the blood vessels causing immediate threat to the hand
High risk of amputation
Needs urgent treatment
Chronic- Gradual decrease in blood flow
Needs treatment of underlying cause
Associated health issues
P.A.D. increases your risk of coronary heart disease, heart attack, stroke, and transient ischemic attack (“mini-stroke”)

Clinical Features
- Weak or absent pulses in the hands
- Intermittent Claudication- symptoms when using the arms and forearms for work which may include pain, numbness, aching, or heaviness in the muscles. Symptoms also may include cramping in the affected side
- Pain in the finger tips even at rest
- Sores or wounds on the fingers that heal slowly, poorly, or not at all
- Gangrene (tissue death)- black color change of skin and tissue
- Infected wounds
- A pale or bluish color to the skin
- A lower temperature in one hand compared to the other hand

Diagnostic Tests
- Doppler Ultrasound
- Stress position tests
- X-rays of neck to see bony abnormalities
- Computerised Tomographic Angiogram (CT Scan)
- Magnetic Resonance Angiogram (MRI Scan)
- Angiogram

Treatment
Treatment is based on your signs and symptoms, risk factors, and the results of physical exams and tests.
Overall goals- improving symptoms and quality of life, ; reducing symptoms of claudication, reduce infection, heal wounds, reducing risk of heart attack, kidney failure and stroke
Target of treatment in Claudicants- improve painfree period
Target of treatment in individuals with wounds/gangrene- remove dead tissue, heal the wound and preserve healthy tissue
Healthy Lifestyle Changes
- Physical activity
- Quitting smoking
- Heart-healthy eating
Treatment options
Bypass Grafting/Embolectomy Surgery- open surgery